Our Team has published seminal findings in the field of exosome biology over the past decade in some of the most prestigious peer-reviewed biomedical journals, including:
NATURE, SCIENCE, CELL & THE JOURNAL OF CLINICAL INVESTIGATION
ACS Nano (2025) Natural and Bioengineered Extracellular Vesicles in Diagnosis, Monitoring and Treatment of Cancer
J Extracell Vesicles (2024) Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Immunity (2024) The biology and function of extracellular vesicles in immune response and immunity
ACS Nano (2024) Single Extracellular Vesicle Imaging and Computational Analysis Identifies Inherent Architectural Heterogeneity
Bioact Mater (2024) High throughput and rapid isolation of extracellular vesicles and exosomes with purity using size exclusion liquid chromatography
J Control Release (2024) Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity
Elife (2024) A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes
bioRxiv (2023) Single extracellular vesicle imaging and computational analysis identifies inherent architectural heterogeneity
bioRxiv (2023) A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes
Biomater Adv (2023) Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells
Cell (2023) The role of extracellular vesicles in cancer
Extracell Vesicle (2022) Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma
Nature Commun (2022) Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
Endocr Rev (2022) Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement
FASEB J (2021) Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis
FEBS J (2021) Exosomes as mediators of immune regulation and immunotherapy in cancer
Life Sci Alliance (2021) Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
Mol Ther Methods Clin Dev (2021) Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer
Life Sci Alliance (2021) Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
Endocrinology (2021) Multifunctional Applications of Engineered Extracellular Vesicles in the Treatment of Cancer
Nature Cell Biology (2021) Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker
Aging (2021) Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release
J Biol Chem (2021) Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity
FASEB J (2021) Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis
Mol Ther Methods Clin Dev (2021) Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer
Cancer Sci (2020) Biology and therapeutic potential of mesenchymal stem cell-derived exosomes
Science (2020) The biology, function, and biomedical applications of exosomes
Trends Cancer (2020) Exosomes as a Multicomponent Biomarker Platform in Cancer
Nature (2020) B cells and tertiary lymphoid structures promote immunotherapy response
Oncogene (2020) Emerging role of bacterial extracellular vesicles in cancer
Cancer Res (2019) Nischarin Regulates Secretion of Exosomes and Cancer Progression
Developmental Cell (2019) SIRT1 Regulates Lysosome Function and Exosome Secretion
Immunity (2019) Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy
Mol Cancer (2019) Mechanisms associated with biogenesis of exosomes in cancer
Genome Med (2018) The emerging roles of exosomes in the modulation of immune responses in cancer
Journal of Clinical Investigation Insight (2018) Generation and testing of clinical-grade exosomes for pancreatic cancer
Oncoimmunology (2018) Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
J Extracell Vesicles (2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
J Extracell Vesicles (2018) Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017
Cancer Biol Ther (2017) Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer
Cancer Res (2017) Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Cell Res. (2017) An evolving function of DNA-containing exosomes in chemotherapy-induced immune response
Nature (2017) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
Cold Spring Harb Symp Quant Biol (2016) Discovery of Double-Stranded Genomic DNA in Circulating Exosomes
Journal of Clinical Investigation (2016) The biology and function of exosomes in cancer
Nature (2015) Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Cancer Cell (2014) Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
J Biol Chem (2014) Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer
J Mol Med (2013) Exosomes in tumor microenvironment influence cancer progression and metastasis
J Am Soc Nephrol (2013) TGF-ß1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis